Achieve better analysis of proteins and their post-translational modifications (PTMs) with the Thermo Scientific™ Electron Transfer Dissociation (ETD) option. Unlike CID, which cleaves weakly bound modifications off the peptide backbone, ETD induces fragmentation along the peptide backbone in a sequence-independent manner, leaving labile modifications linked to the peptide chain. This greatly simplifies identification of modification sites. ETD produces primarily c- and z-type fragment ions that complement the b- and y-type ions produced by CID, increasing sequence coverage and protein IDs.

Electron transfer dissociation is a supremely useful tool for the analysis of post-translationally modified proteins. ETD capability can be added to many Thermo Scientific™ ion trap and Orbitrap™ mass spectrometers. Thermo Scientific™ Proteome Discoverer™ software includes unique capabilities to help users take full advantage of the information provided by ETD.

ETD preserves labile PTMs, allowing straightforward identification of the peptide sequence and the site of modification
For top-down analysis, ETD can be combined with proton transfer reaction (PTR) which dramatically simplifies spectra from intact proteins
For workflows that include low-mass isobaric mass tags, ETD can be combined with pulsed-Q dissociation (PQD) which eliminates the normal low-mass cutoff
ETD can be added to most Thermo Scientific LTQ-series ion trap and hybrid ion trap-Orbitrap mass spectrometers
Proteome Discoverer software includes the proprietary Z-Core database search algorithm specifically optimized for ETD spectra
Proteome Discoverer software can easily merge complementary CID and ETD results to maximize protein sequence coverage

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Quality

Our refurbished instruments are tested and repaired to meet factory specifications. We follow Installation Qualification, Operational Qualification, and Performance Qualification protocols (IQ, PQ and OQ).

Expertise

Our team of skilled technicians are experts at fixing analytical instruments. We have been working with Agilent, Waters, Perkin Elmer, Sciex, Shimadzu, and Thermo instruments for many years. We are constantly updating our knowledge with the latest technology and information to enable us to deliver the best support in the industry. We provide value added support and qualification/validation with all our instruments. We endeavor to develop strategic partnerships with our clients so that they consider our team as an extension of their employees. We are an affordable alternative to many normally expensive business projects.

Warranty and Support

We offer warranty on all refurbished instruments. Warranty starts at 3 months, with the option to extend the period. While your instrument is on warranty, we will provide Email ([email protected]) and phone support and troubleshooting if you require assistance. If there is ever anything wrong with the equipment, we will replace it. Warranty begins from the date your equipment is successfully delivered. Any issues that occur during warranty should be reported immediately, describing the issues in as much detail as possible. Do not attempt to repair the equipment or involve a 3rd party without our express permission – this will result in voiding our warranty.

We will match our warranty duration with our competitors.

Installation and Training

If you purchase equipment from Spectralab Scientific, we offer installation and familiarization by our service technicians for an additional fee. If the instrument is particularly complicated, we highly recommend this service. If you’ve purchased less-complex equipment from us that you would like to install yourself, we can provide Team Viewer, email, or telephone support for no additional cost.

Large Inventory

We have a large inventory of equipment, components and parts in stock. You can find all the equipment you need for you lab in our store, as well as mix and match components for your systems.

International Shipping

We have sufficient export experience, including professional packing and proper documentation. Complementary shipping and handling can be applied upon immediate purchase. We include customs fees, brokerage, and duties for shipping to the US.

Price Matching & Discounts

Purchasing our refurbished instruments can save you anywhere from 30% to 90% compared to purchasing brand new. We will try to match or beat any price from our competitors, so feel free to inquire! Complementary shipping and handling can be applied upon immediate purchase.