Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer (2018)

Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer (2018)
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Condition: Refurbished

Availability: In Stock

Manufacturer: Thermo Fisher ScientificPrice:

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Warranty Included, Onsite/ Remote Installation and Training Available


CAN/US: 3-5 business days
International: 5-10 business days

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Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer 2018 model. A rough pump and PC with data is included. We can add any suitable UHPLC/HPLC to this MS system.

Performance Characteristics
Resolution 240,000 at m/z 200
Mass range 50 to 6,000 m/z
Scan rate* Up to 40 Hz at resolution setting of 7,500 at m/z 200
Mass accuracy* Internal: < 1 ppm RMS

External: < 3 ppm RMS

Sensitivity MS/MS: 100 fg reserpine on column S/N 150:1

SIM: 50 fg reserpine on column S/N 150:1

Dynamic range > 5,000:1
Polarity switching One full cycle in < 1 sec (one full positive mode scan and one full negative mode scan at a resolution setting of 60,000)
Multiplexity Up to 10 precursors/scan
Analog inputs One (1) analog input (0–1 V)

One (1) analog (0–10 V)

Experience the cutting-edge capabilities of the Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap MS System. This advanced mass spectrometer combines innovative technologies to deliver unmatched speed, sensitivity, and precision in identification and quantitation.

Unparalleled Performance: With its high-resolution, accurate-mass (HRAM) ultra-high-field Orbitrap mass analyzer, the Q Exactive HF-X MS ensures exceptional results across a wide range of applications. Achieve maximum resolving power of up to 240,000 (FWHM) at m/z 200, allowing for confident structural confirmation in biopharmaceutical and omics studies. The system offers superior performance in peptides, proteins, and small molecule analysis.

Enhanced Speed and Sensitivity: Experience the power of accelerated Higher-Energy Collisional Dissociation (aHCD) capabilities, enabling MS/MS acquisition at an impressive speed of up to 40 Hz. The advanced quadrupole technology (AQT) optimizes precursor ion selection and transmission, enhancing quantitation of low-abundant ions even in the most complex matrices. The high capacity transfer tube (HCTT) and electrodynamic ion funnel improve sensitivity, ensuring efficient ion flux and desolvation.

Advanced Acquisition Strategies: The Q Exactive HF-X MS features a new Data Dependent Acquisition (DDA) strategy for both bottom-up and top-down proteomics analysis. Benefit from dynamic retention time adjustment in PRM, enabling superior targeted quantitation. Additionally, sophisticated Parallel Reaction Monitoring and Data-Independent Acquisition (DIA) methods provide reproducible quantitation results and qualitative confidence.

BioPharma Option: Take your analysis to the next level with the BioPharma option. This enhanced feature enables comprehensive analysis of intact proteins, protein-protein complexes, mAb subunits, and intact mAb. It includes Intact Protein Mode and High Mass Range (HMR) mode, catering to the specific needs of native protein or protein complex characterization, as well as peptide mapping.

Cutting-Edge Hardware Specification: The Q Exactive HF-X MS is equipped with top-of-the-line hardware components for optimal performance and reliability. The Thermo Scientific Ion Max API Source includes an H-ESI II probe with dual desolvation zone technology, offering enhanced sensitivity and ruggedness. The High Capacity ion Transfer Tube (HCTT) and Electrodynamic Ion Funnel (EDIF) ensure improved ion flux, efficient ion capture, and reduced losses. The Advanced Quadrupole Technology (AQT) with a segmented Thermo Scientific HyperQuad mass filter provides superior ion transmission and isolation window shape.

Unmatched Data Acquisition: Experience ultra-fast real-time data acquisition and instrument control with the Q Exactive HF-X MS. The fully automated system calibration via instrument control software ensures accuracy and reliability. The Automatic Gain Control (AGC) support optimizes signal intensity for precise measurements.

Discover the Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap MS System and unlock the true potential of your analytical research. Achieve exceptional results with unrivaled speed, sensitivity, and confidence in your analyses.

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Our refurbished instruments are tested and repaired to meet factory specifications. We follow Installation Qualification, Operational Qualification, and Performance Qualification protocols (IQ, PQ and OQ).

Our team of skilled technicians are experts at fixing analytical instruments. We have been working with Agilent, Waters, Perkin Elmer, Sciex, Shimadzu, and Thermo instruments for many years. We are constantly updating our knowledge with the latest technology and information to enable us to deliver the best support in the industry. We provide value added support and qualification/validation with all our instruments. We endeavor to develop strategic partnerships with our clients so that they consider our team as an extension of their employees. We are an affordable alternative to many normally expensive business projects.

Warranty and Support
We offer warranty on all refurbished instruments. Warranty starts at 3 months, with the option to extend the period. While your instrument is on warranty, we will provide Email ( and phone support and troubleshooting if you require assistance. If there is ever anything wrong with the equipment, we will replace it. Warranty begins from the date your equipment is successfully delivered. Any issues that occur during warranty should be reported immediately, describing the issues in as much detail as possible. Do not attempt to repair the equipment or involve a 3rd party without our express permission – this will result in voiding our warranty.

We will match our warranty duration with our competitors.

Installation and Training
If you purchase equipment from Spectralab Scientific, we offer installation and familiarization by our service technicians for an additional fee. If the instrument is particularly complicated, we highly recommend this service. If you’ve purchased less-complex equipment from us that you would like to install yourself, we can provide Team Viewer, email, or telephone support for no additional cost.

Large Inventory
We have a large inventory of equipment, components and parts in stock. You can find all the equipment you need for you lab in our store, as well as mix and match components for your systems.

International Shipping
We have sufficient export experience, including professional packing and proper documentation. Complementary shipping and handling can be applied upon immediate purchase. We include customs fees, brokerage, and duties for shipping to the US.

Price Matching & Discounts
Purchasing our refurbished instruments can save you anywhere from 30% to 90% compared to purchasing brand new. We will try to match or beat any price from our competitors, so feel free to inquire! Complementary shipping and handling can be applied upon immediate purchase.

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