Q Exactive HF-X Quadrupole-Orbitrap Mass Spectrometer

The Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap mass spectrometer combines a high-resolution, accurate-mass (HRAM) ultra-high-field Orbitrap mass analyzer, high capacity transfer tube with electrodynamic ion funnel and high performance quadrupole precursor ion selection to deliver unsurpassed speed and first class sensitivity.

The Q Exactive HF-X MS takes identification and quantitation to an unmatched level, making it possible to identify, quantify, and confirm in a single analysis with a single instrument.

The Q Exactive HF-X MS provides best-in-class performance in peptides, proteins, and small molecule applications. Accelerated Higher Energy Collisional Dissociation (aHCD) allows for MS/MS acquisition up to 40Hz. Advanced Quadrupole Technology (AQT) optimizes precursor ion selection and transmission, improving quantitation of low-abundant ions in the most complex matrices. Sophisticated Parallel Reaction Monitoring and Data-Independent Acquisition (DIA) methods provide reproducible quantitation results while delivering complete qualitative confidence. 240,000 maximum resolving power at m/z 200 (FWHM), ensures more confident structural confirmation in biopharma and omics applications. The new BioPharma option adds superior capabilities when it comes to the analysis of native proteins or protein complexes and their subunits (top/middle-down), and peptide mapping characterization.

Features:

• Scan speed up to 40 Hz with ultra-high-field Thermo Scientific Orbitrap mass analyzer technology
• Resolution of up to 240,000 (FWHM) at m/z 200
• High Capacity Transfer Tube (HCTT) and electrodynamic ion funnel for improved sensitivity
• Advanced Quadrupole Technology (AQT) for superior precursor isolation
• Advanced Active Beam Guide (AABG) for greater sensitivity and maximum robustness
• New Data Dependent Acquisition (DDA) strategy for bottom-up and top-down proteomics analysis
• Dynamic retention time adjustment in PRM for superior targeted quantitation
• Accelerated Higher-Energy Collisional Dissociation (aHCD) capabilities
• BioPharma option for enhanced analysis of intact proteins, protein-protein complexes, mAb subunits, and intact mAb. Includes Intact Protein Mode and High Mass Range (HMR) mode.

EASY-nLC 1000

The Thermo Scientific EASY-nLC 1000 provides effortless split-free, nano-flow UHPLC performance up to 1000 bar with minimal investment. Dual in-line flow sensors before mixing gives uncompromising gradient precision.

Features:

Advanced Flow Control
• Intelligent Flow Control (IFC) during loading and equilibration provides robust performance and protects against blocked columns
• Advanced Flow Control (AFC) during gradients provides outstanding reproducibility, sample to sample and over time

Intelligent Maintenance
• Automated, built-in maintenance steps
• Remote access via internet for system interrogation
• Event log for troubleshooting
• Automated leak test indicates actual position of leak
• System back pressure test quickly detects flow-line blockage

Integrated Design with Built-in PC
• Intuitive control from touch screen interface
• Structured layout for easy component exchange
• Pulsation-free pumps minimize need for replacement of seals, valves and fittings
• Optimized flow paths are utilised by software
• Easy maintenance, access and service

Stable, Pulsation-free Gradients from 100 nL/min
• Factory-configured flow paths minimize swept volume
• Maximum chromatographic accuracy with:
– Split-free gradient mixing
– Step-controlled nano-flow syringe pumps
– Flow sensor control of mobile phase delivery

System Includes:

Q Exactive HF-X Quadrupole-Orbitrap Mass Spectrometer
EASY-nLC 1000
Chemyx Fusion 100T2 Syringe Pump
Agilent MS120 Single Stage Rotary Vane Pump
PC with xCalibur software

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Quality

Our refurbished instruments are tested and repaired to meet factory specifications. We follow Installation Qualification, Operational Qualification, and Performance Qualification protocols (IQ, PQ and OQ).

Expertise

Our team of skilled technicians are experts at fixing analytical instruments. We have been working with Agilent, Waters, Perkin Elmer, Sciex, Shimadzu, and Thermo instruments for many years. We are constantly updating our knowledge with the latest technology and information to enable us to deliver the best support in the industry. We provide value added support and qualification/validation with all our instruments. We endeavor to develop strategic partnerships with our clients so that they consider our team as an extension of their employees. We are an affordable alternative to many normally expensive business projects.

Warranty and Support

We offer warranty on all refurbished instruments. Warranty starts at 3 months, with the option to extend the period. While your instrument is on warranty, we will provide Email (support@spectralabsci.com) and phone support and troubleshooting if you require assistance. If there is ever anything wrong with the equipment, we will replace it. Warranty begins from the date your equipment is successfully delivered. Any issues that occur during warranty should be reported immediately, describing the issues in as much detail as possible. Do not attempt to repair the equipment or involve a 3rd party without our express permission – this will result in voiding our warranty.

We will match our warranty duration with our competitors.

Installation and Training

If you purchase equipment from Spectralab Scientific, we offer installation and familiarization by our service technicians for an additional fee. If the instrument is particularly complicated, we highly recommend this service. If you’ve purchased less-complex equipment from us that you would like to install yourself, we can provide Team Viewer, email, or telephone support for no additional cost.

Large Inventory

We have a large inventory of equipment, components and parts in stock. You can find all the equipment you need for you lab in our store, as well as mix and match components for your systems.

International Shipping

We have sufficient export experience, including professional packing and proper documentation. Complementary shipping and handling can be applied upon immediate purchase. We include customs fees, brokerage, and duties for shipping to the US.

Price Matching & Discounts

Purchasing our refurbished instruments can save you anywhere from 30% to 90% compared to purchasing brand new. We will try to match or beat any price from our competitors, so feel free to inquire! Complementary shipping and handling can be applied upon immediate purchase.