This system includes:
- Xevo TQ-S Micro Triple Quadrupole Mass Spectrometer
- Atmospheric Pressure Gas Chromatography (APGC) Interface
- QSM Quaternary Solvent Manager
- SM-FTN-H Sample Manager
- CH-A Column Heater
- Agilent 8890 Gas Chromatograph (GC)
- Agilent 7693A Liquid Autosampler
- PC with data
- Rough pump
The Waters Xevo TQ-S Micro LC-MS/MS System configured with the Waters ACQUITY H-Class UPLC System and Agilent 8890 Gas Chromatograph with Agilent 7693 Autosampler delivers a highly flexible analytical platform combining advanced LC-MS/MS sensitivity with automated gas chromatography capabilities. Inspired by Waters’ Atmospheric Pressure Gas Chromatography (APGC) technology, this integrated configuration expands analytical versatility by supporting both liquid and gas chromatography workflows on a powerful tandem quadrupole mass spectrometry platform.
The Xevo TQ-S Micro is designed to provide robust quantitative performance, exceptional sensitivity, and reliable operation in a compact footprint. Featuring Waters’ StepWave ion transfer optics and high-efficiency ionization technology, the system delivers improved ion transmission while minimizing neutral contamination for enhanced analytical stability and low detection limits. Its fast Multiple Reaction Monitoring (MRM) acquisition rates and advanced tandem quadrupole design make it ideal for trace-level compound analysis in complex sample matrices.
Paired with the Waters H-Class UPLC, the platform offers precise solvent delivery, high-pressure separations, and reproducible chromatographic performance for demanding LC-MS applications. The addition of the Agilent 8890 GC with 7693 autosampler provides automated gas chromatography analysis with reliable sample introduction and high-throughput operation.
Drawing from Waters APGC capabilities, the system is particularly well suited for compounds traditionally challenging for conventional ionization techniques, enabling soft ionization with reduced fragmentation and enhanced molecular ion detection. This improves confirmation and identification of semi-volatile and non-polar compounds across a wide range of analytical workflows.



